Migraine is a common headache disorder characterized by recurrent attacks of mild to severe throbbing – sometimes pulsation sensations. The pain is usually on one side of the head but can occur in any region. Pain can be associated with sensitivity to light, noise and odors. Additionally, patients may experience nausea and/or vomiting. Headaches are often worsened by movement and or physical activity.

The two major types are Migraine with Aura and Migraine without Aura. Subtypes include Basilar Type Migraine, Hemiplegic Migraine and Menstrual Migraine. The prevalence of a migraine in women and in men has been reported as 17% and 6%, respectively.

Etiology of migraine can vary and include genetic factors, cerebral vasodilation, magnesium deficiency, and increase in calcitonin gene-related peptide and neurogenic inflammation. During the acute phase of this disease there may be a release of proinflammatory peptides.

Multiples clinical studies have proved efficacy in use of anti-inflammatory nutrients such as omega-3 fatty acids, EPA and DHA to inhibit the production of inflammatory proteins. These nutrients act to modify immune reactions to reduce inflammation.

In conclusion, Omega – 3 fatty acids, can be considered as an adjunctive therapy for patients with Migraine disorder. Omega 3 – fatty acids can potentially reduce the inflammatory response during a migraine attack which in turn may help alleviate symptoms.

By: Jordan Shankle, PA